Erythema nodosum - 結節性紅斑
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ドイツの2022年Stiftung Warentestの結果では、ModelDermに対する消費者満足度は有料の遠隔医療相談よりもわずかに低いだけでした。
ドイツの2022年Stiftung Warentestの結果では、ModelDermに対する消費者満足度は有料の遠隔医療相談よりもわずかに低いだけでした。
脚に、痛みを伴う紅斑性結節として現れます。
relevance score : -100.0%
ReferencesErythema nodosum は、最も一般的なタイプの脂肪織炎で、主に下肢に見られる痛みを伴う赤い結節が特徴です。その正確な原因はまだ不明ですが、さまざまな引き金に対する過剰な免疫反応が関与していると考えられます。原因が特定できないことが多いですが、primary erythema nodosum と診断する前に、他の基礎疾患を除外することが重要です。基礎疾患としては、感染症、炎症性疾患、がん、薬剤への反応などがあり、全身性疾患の兆候である可能性があります。一般的なトリガーには、strep infections、tuberculosis、sarcoidosis、Behçet’s disease、inflammatory bowel disease、特定の薬剤、妊娠が含まれます。
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis は、皮膚の下にある脂肪組織に影響を及ぼすさまざまな炎症状態を指します。小児でこの疾患が現れることはまれです。Panniculitis は、全身性疾患の主要な症状として現れることもあれば、感染、外傷、特定の薬剤などが原因となる二次的な反応であることもあります。原因に関わらず、ほとんどの panniculitis は皮膚の下に痛みを伴う赤い結節を呈し、同様の症状がみられます。
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis は皮膚の下にある脂肪層の炎症で、通常は腫れた小結節や斑点として現れるまれな症状です。Erythema nodosum (EN) は最も一般的なタイプで、さまざまな要因によって引き起こされます。症例の約55 %には明確な原因が認められませんが、主な誘因としては感染症、薬剤、サルコイドーシスや炎症性腸疾患などの特定の疾患、妊娠、がんなどが挙げられます。EN は主に10代から若年成人に発症し、女性に多く見られます。多くの場合、発熱や上気道症状などを伴う全身の倦怠感が 1～3 週間続き、その後、腕や脚の外側に赤い結節が出現し、痛みを伴います。EN の正確な原因は完全には解明されていませんが、脂肪層の小血管内に免疫複合体が沈着し、炎症を引き起こすと考えられています。生検では血管損傷は認められず、脂肪層の炎症が確認されます。根本的な原因に対する特別な治療を行わなくても、EN は自然に改善することが多く、ほとんどの患者は症状に対する対症療法のみで十分です。
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
結節性紅斑は臨床所見で診断されますが、診断が不確かな場合は生検を行い、顕微鏡検査で確認することができます。肺疾患、特にサルコイドーシスや結核を除外するために胸部X線検査が必要です。